|
KMID : 1011320200120010029
|
|
Journal of Pharmacoepidemiology and Risk Management
2020 Volume.12 No. 1 p.29 ~ p.35
|
|
|
Establishment of Contrast Media Safety & Management Office at a Single Hospital
|
|
Kim Sung-Ryeol
Park Kyung-Hee
Hong Yoo-Jin
Oh Young-Taik
Park Jung-Won
Lee Jae-Hyun
|
|
|
Abstract
|
|
|
Objective: Establishment of contrast media safety & management office at a single hospital to manage immediate adverse
drug reactions (ADRs) by contrast media used in computed tomography (CT).
Methods: The contrast media safety & management office was established near the CT examination room in Severance Hospital in November 2018, and a nurse was assigned to be in charge of the office. Patients with history of immediate ADR to CT contrast media were registered with this office and provided management support; those with a history of moderate to severe reactions underwent a skin test using the contrast media. The results of the skin test were used for selecting alternative contrast media. In addition, a window warning about the immediate ADR to contrast media was programed to appear on the electric medical program so that adverse reactions could be known in advance and prevented.
Results: The frequency of immediate ADR to contrast media significantly decreased in 2019 compared to that in 2018 (0.41% vs. 0.60%, p＜ 0.001). The percentages of moderate to severe adverse reactions (23.0% vs. 18.9%) and breakthrough reactions (8.2% vs. 7.3%) were decreased compared to the respective percentages in 2018.
Conclusion: Severance contrast media safety & management office has been helping to reduce immediate ADRs through systemically managing patients who had previously experienced ADRs to contrast media.
|
|
|
KEYWORD
|
|
|
Contrast media, Skin prick test, Intradermal test, Safety & management office, Premedication
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|